What is it about?

The obligate intracellular bacteria Chlamydia trachomatis is a human pathogen of global importance (eye infection causing trachoma and urogenital tract infection leading to infertility). Infectious bacteria cell surface present a group of nine polymorphic membrane proteins (Pmp) which act as adhesins and are essential for the infection of human cells.

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Why is it important?

Chlamydia trachomatis polymorphic membrane proteins are located on the bacterial cell surface, act as adhesins and are important for the infection. This makes them prime candidates for the development of a subunit vaccine which currently is not available.

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This page is a summary of: All subtypes of the Pmp adhesin family are implicated in chlamydial virulence and show species‐specific function, MicrobiologyOpen, July 2014, Wiley,
DOI: 10.1002/mbo3.186.
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