AglB, catalyzing the oligosaccharyl transferase step of the archaealN-glycosylation process, is essential in the thermoacidophilic crenarchaeonSulfolobus acidocaldarius

Benjamin H. Meyer, Sonja-Verena Albers
  • MicrobiologyOpen, June 2014, Wiley
  • DOI: 10.1002/mbo3.185

N-glycosylation is essential in Sulfolobus acidocaldarius

What is it about?

Many extracellular proteins of Archaea are N-glycosylated. In some euryarchaea it was shown that N-glycosylation is not essential. We wanted to test whether this is the same for Sulfolobus acidocadarius.

Why is it important?

The result showed that in contrast to the other archaeal examples in S. acidocaldarius N-glycosylation is essential and interestingly resembles the first steps of eukaryal N-glycosylation pathway.

Read Publication

http://dx.doi.org/10.1002/mbo3.185

The following have contributed to this page: Professor Sonja-Verena Albers