What is it about?
Many extracellular proteins of Archaea are N-glycosylated. In some euryarchaea it was shown that N-glycosylation is not essential. We wanted to test whether this is the same for Sulfolobus acidocadarius.
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Why is it important?
The result showed that in contrast to the other archaeal examples in S. acidocaldarius N-glycosylation is essential and interestingly resembles the first steps of eukaryal N-glycosylation pathway.
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This page is a summary of: AglB, catalyzing the oligosaccharyl transferase step of the archaealN‐glycosylation process, is essential in the thermoacidophilic crenarchaeonSulfolobus acidocaldarius, MicrobiologyOpen, June 2014, Wiley,
DOI: 10.1002/mbo3.185.
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