What is it about?
This is an updated review about applications of LA-ICP-MS (inorganic mass spectrometry) in biomedical research.
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Why is it important?
The distribution analysis of elements in biological samples is a key point of interest in life sciences, especially within the context of metallomics, which is the scientific field that encompasses the global analysis of the entirety of elemental species inside a cell or tissue.
Perspectives
Determination and visualization of elemental distribution within a biological tissue by mass spectrometry imaging can help to understand disease and/or treatment mechanisms and further propose possible biomarkers. Metalloproteomics is also an important strategy in the same context. For both strategies, LA-ICP-MS is a very powerful analytical technique that can be applied.
Professor Alessandra Sussulini
University of Campinas
Read the Original
This page is a summary of: Laser ablation ICP-MS: Application in biomedical research, Mass Spectrometry Reviews, September 2015, Wiley,
DOI: 10.1002/mas.21481.
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