What is it about?

Many pharmaceuticals represent a multi component mixture of active and non active ingredients having different properties. Ideally, it would be good to determine all of them in a single step analysis. In this particular paper it was done by using mixed mode chromatography, when different substances/ions are retained by a single chromatographic column and therefore their content can be quantified.

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Why is it important?

The analysis can be performed in a shorter time with a single instrument.

Perspectives

There are many other applications can be considered for the proposed chromatographic system

Professor Pavel N Nesterenko
M.V. Lomonosov Moscow State University

Read the Original

This page is a summary of: Comprehensive analysis of pharmaceutical products using simultaneous mixed-mode (ion-exchange/reversed-phase) and hydrophilic interaction liquid chromatography, Journal of Separation Science, June 2014, Wiley,
DOI: 10.1002/jssc.201400411.
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