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The chronic inhibition of synapsin decreased synaptogenesis and increased neurotransmitter release and synaptic fatigue under high frequency stimulation without affecting basal synaptic transmission on simple monosynaptic circuits.
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This page is a summary of: Synapsin knockdown is associated with decreased neurite outgrowth, functional synaptogenesis impairment, and fast high-frequency neurotransmitter release, Journal of Neuroscience Research, July 2015, Wiley,
DOI: 10.1002/jnr.23624.
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