What is it about?
To assess with magnetic resonance imaging (MRI) adriamycin-induced nephropathy in living rats, an established model for proteinuric renal disease was used.
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Why is it important?
MRI provides longitudinal functional and cellular (macrophage infiltration) information that correlates with nephropathy development in adriamycin-challenged rats.
Perspectives
Excellent model to test anti-fibrotic compounds.
Professor Nicolau Beckmann
Novartis Institutes for BioMedical Research Basel
Read the Original
This page is a summary of: Adriamycin-induced nephropathy in rats: Functional and cellular effects characterized by MRI, Journal of Magnetic Resonance Imaging, March 2014, Wiley,
DOI: 10.1002/jmri.24603.
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