What is it about?

The article explains the regio-selectivity in addition of several enaminonitriles and enaminones to 2-amino-1,2,4-triazole.

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Why is it important?

The issue of regio-selectivity reaction of electrophiles with 2-amino-1,2,4-triazoles still unsolved issue and no general rules have been established. The article shed further light to such problem

Perspectives

Publishing this article with colleges in Kuwait was a great task as it removes barriers and establishes a base of cooperation between scientists in different countries. In addition the problem was interest and deserve efforts spent in achieving results

Professor Kamal Usef Sadek
Chemistry Department,Faculty of Science,Minia University, Egypt

Read the Original

This page is a summary of: Synthesis of New [1,2,4]Triazolo[1,5-a ]pyrimidine Derivatives: Reactivity of 3-Amino[1,2,4]triazole towards Enaminonitriles and Enaminones, Journal of Heterocyclic Chemistry, June 2018, Wiley,
DOI: 10.1002/jhet.3222.
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