What is it about?
The patients were asymptomatic and had not any hepatocarcinogenic factor, and hepatic function was almost normal in most cases. HCC was all large, encapsulated and solitary and predominantly well-differentiated or moderately differentiated in most cases. US showed a hypoechoic marginal rim and lateral shadowing, suggestive of peritumoral capsule formation, and on contrast-enhanced US (CEUS), the HCC lesion was hyperenhanced in arterial phase and washed-out in postvascular phase, revealing typical HCC findings.
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Why is it important?
US increases the possibility of HCC in otherwise sonographycally normal liver, by showing lateral shadowing (grayscale ultrasound) and hypervascularity (CEUS) of the lesion.
Perspectives
The role of US in the diagnosis of HCC on normal liver is thought to consist of the following; detection of the lesion, visualization of a peritumoral capsule, and confirmation of the hypervascularity of the lesion in arterial phase, and demonstration of wash-out of the lesion in postvascular phase. These three points help to diagnose the lesion to be HCC, even if US detects a mass lesion in elderly patients without hepatic dysfunction or a hepatocarcinogenic factor.
Dr Hiroko Naganuma
Yokote Municipal Hoapital
Read the Original
This page is a summary of: Hepatocellular carcinoma in otherwise sonographically normal liver, Journal of Clinical Ultrasound, November 2018, Wiley,
DOI: 10.1002/jcu.22677.
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