What is it about?
This new protocol shows an efficient combination of calcium+IBMX+Insulin to induce differentiation of human mesenchymal stem cells into neuron-like cells. The protocol is simple and economic in compare with other protocol that have used growth factors.
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Why is it important?
Calcium is always considered as a major component of normal neuronal function. However, in this study we have shown that it also has other side than it seems. Although, the role of calcium was elucidated in fetal neurogenesis, calcium differentiating capacity for the neuron-like cells was never investigated.
Perspectives
To me this work was an inflection point for observing the science not as a complicating process as always.
Dr Farjam Goudarzi
Hamadan University of Medical Sciences
Read the Original
This page is a summary of: Calcium: A novel and efficient inducer of differentiation of adipose-derived stem cells into neuron-like cells, Journal of Cellular Physiology, June 2018, Wiley,
DOI: 10.1002/jcp.26826.
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