What is it about?
Thrombotic thrombocytopenic purpura (TTP) is very unlikely to occur in patients with Bernard-Soulier syndrome.
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Why is it important?
TTP drugs such as caplacizumab are unlikely to work in patients with Bernard-Soulier syndrome.
Perspectives
A trick for remembering the pathogenesis of both conditions by understanding that "BSS protects against TTP."
Ryan Jajosky
Augusta University
Read the Original
This page is a summary of: Does Bernard-Soulier syndrome protect against thrombotic thrombocytopenic purpura?, Journal of Clinical Apheresis, June 2017, Wiley,
DOI: 10.1002/jca.21564.
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