Non-invasive label-free quantification method of collagen

What is it about?

Punch biopsy followed by microscopy is an invasive technique still considered to be the gold standard for assessment of burn wound healing. In the present study, we have reported an autofluorescence based non-invasive, pain-free approach to quantify collagen during burn wound healing. This study demonstrated collagen as an optical biomarker for assessing burn wound healing

Featured Image

Why is it important?

This technique quantifies the collagen in healing tissue thereby provides the healing status in real time. The technique is also user-friendly solely dependent on excitation and emission of tissue fluorophores without the addition of any external dye molecule thus maintaining tissue architecture during the measurement.

Perspectives