What is it about?
Studying pathways we can understand how a drug cause toxicity. We can identify a key event and stop it. So, we can avoid toxicity.
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Why is it important?
It is paramount understand molecular target to understand a toxic effect. It will help develop a new drug.
Perspectives
It is important to study molecular target in order to develop safer drugs. Nowadays, this process has become useful among pharmaceuticals industries to develop new medicines. Thus, we can find out toxic effet earlier.
Professor CARLOS ALBERTO TAGLIATI
FEDERAL UNIVERSITY
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This page is a summary of: Alteration in cellular viability, pro-inflammatory cytokines and nitric oxide production in nephrotoxicity generation by Amphotericin B: involvement of PKA pathway signaling, Journal of Applied Toxicology, September 2013, Wiley,
DOI: 10.1002/jat.2927.
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