What is it about?

Men with low Prostate-Specific Antigen levels are thought to have low risk of developing prostate cancer. This study examines the risk of prostate cancer development in these men and found substantial rate of incidence among them. We also identify the factors that play significant roles in this.

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Why is it important?

Our findings shows that low PSA level alone is not enough to rule out risk of development of prostate cancer and that the risk increases as PSA levels increase. Current PSA screening system need to be improved to increase its accuracy while avoiding overdiagnosis and other complications.


I hope this article reiterates the need to have more comprehensive and efficient prostate cancer screening system that eliminates the risks and improve early detection of clinically-relevant prostate cancer.

Dr. Idris Olasunmbo Ola
University of Gothenburg, Gothenburg, Sweden

Read the Original

This page is a summary of: Prostate cancer incidence in men with prostate‐specific antigen below 3 ng/ mL : The Finnish Randomized Study of Screening for Prostate Cancer, International Journal of Cancer, September 2022, Wiley,
DOI: 10.1002/ijc.34274.
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