What is it about?
For a new memory to be consolidated in a way it can be remembered sometime afterward, it requires not only new protein synthesis, but new mRNA synthesis, what demands much more energy from neuronal biochemical machinery. And the same is true for a already saved memory to be maintained right after it is remembered.
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Why is it important?
The fact that a given memory needs new mRNA synthesis to be maintained right after to be remembered opens the possibility for a selective manipulation, this is, strengthening or weaking, of this memory, according to the specific moment it is remembered.
Perspectives
This publication support the subsequent research for what genes have their transcription rate modified by retrieval, in order we to be able to better understand how memories are stored, maintained and modified along the time and due to retrieval circumstances.
Ph.D. Weber Claudio Da Silva
Universidade Estadual do Centro-Oeste
Read the Original
This page is a summary of: Inhibition of mRNA synthesis in the hippocampus impairs consolidation and reconsolidation of spatial memory, Hippocampus, January 2007, Wiley,
DOI: 10.1002/hipo.20362.
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