What is it about?
As an expert in biomedical research, life sciences and public health research with high-quality academic research experience from New York, Texas, Nebraska, USA, i feel that bioethics and good practice clinical research should be coupled with scientific exchange of knowledge for elegantly bridging the gap in data-sharing /data-interpretation amongst emerging as well as established authors worldwide. My article certainly add to the advanced biomedical research inteelectual pool with critical insights in NAFLD pathogenesis. Ethnicity, age, lifestyle are significant predictors of disease susceptibility and therefore cost-effective public health research models in hepatology, viz. liver fibrosis, hepatocellular carcinoma, NAFLD, NASH, and even colorectal carcinoma are warranted to significantly reduce the increasing burden of hepatic disorders worldwide.
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Why is it important?
I have provided the public health significance of NAFLD; future pharmacogenetic studies and animal models of diseases may be collaboratively designed for deriving more definitive conclusions.
Perspectives
My personal perspective regarding my recently published article: the complex disease-web needs to be demystified and the regulatory signal transduction networks targeted for eventual design of patient-friendly, cost-effective biomarkers for management of NAFLD and interrelated hepatic ailments including colorectal cancer in ethnically disparate populations worldwide. Inflammation, carcinogenesis and metabolic signaling, including autophagy and ceramide-mediated apoptosis/cell death happen to be attractive immunotherapeutic ares for deciphering the clinical sequela and cellular/molecular mechanisms and genetic basis of NAFLD. DR. SAUMYA PANDEY PH.D. drsaumyapandey11@gmail.com Lucknow, India; December 12, 2018.
DR. SAUMYA PANDEY
Read the Original
This page is a summary of: Association of Nonalcoholic Fatty Liver Disease With Relative Skeletal Muscle Mass: APublic Health Perspective, Hepatology, October 2018, Wiley,
DOI: 10.1002/hep.30107.
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