What is it about?
ATGL deficiency by modifying lipid synthesis in the liver reduces ER stress in an acute model induced by tunicamycin
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Why is it important?
ATGL was shown to protect the liver in NAFLD, but for the first time ATGL deficiency is hepato protective by reducing ER stress a late NASH stage disease
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This page is a summary of: Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice, Hepatology, May 2012, Wiley,
DOI: 10.1002/hep.25601.
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