What is it about?

We develop a valuation model of the option to withhold wide use of an antibiotic until significant outbreaks such as pandemic influenza or foodborne diseases are identified. Using real options theory, we derive conditions under which withholding wide use is beneficial, and calculate the option value for influenza pandemic scenarios that lead to secondary infections with a resistant Staphylococcus aureus strain. We find that the value of withholding an effective novel oral antibiotic can be positive and significant unless the pandemic is mild and causes few secondary infections with the resistant strain or if most patients can be treated intravenously.

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Why is it important?

Provides with the help of a model the possibility to assess alternative control strategies for pandemics. Important for the current debate on the corona virus.

Perspectives

I hope researchers will continue improving the model by adding additional details, in particular for addressing the current corona crisis.

Professor Justus Wesseler
Wageningen Universiteit en Researchcentrum

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This page is a summary of: Investing in antibiotics to alleviate future catastrophic outcomes: What is the value of having an effective antibiotic to mitigate pandemic influenza?, Health Economics, February 2019, Wiley,
DOI: 10.1002/hec.3867.
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