What is it about?

A study demonstrating how a protein is required for brain development and function

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Why is it important?

this protein is required for formation of the insulating membrane on neuronal axons (cables-like) required for fast transmission of information in the nervous system

Perspectives

It is the first demonstration that Cdon is involved in differentiation of oligodendrocytes, a type of neural cell that forms myelin. Although, further studies are required to investigate the mechanism(s) by which Cdon is involved in OLG differentiation and myelination, our results provide a solid basis for future investigation of its role in remyelination and CNS repair in demyelinating diseases

Dr. Guillermina Almazan
McGill University

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This page is a summary of: Cdon, a cell surface protein, mediates oligodendrocyte differentiation and myelination, Glia, March 2016, Wiley,
DOI: 10.1002/glia.22980.
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