Summary of strategies to study interactions between surfaces and amino acids/peptides

What is it about?

Amino acids and peptides are important biomolecules and represent the building blocks of proteins. Amino acid/peptide interactions with inorganic materials interplay in several systems within the human body or even for the evolution of life on earth. Here, we review different experimental techniques as well as simulation approaches how these interactions can be investigated. Therefore we highlight the advantages and disadvantages of each technique.

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Why is it important?

The study of interactions between amino acids/peptides and inorganic surfaces paves the way for a fundamental understanding of inorganic-organic interactions. This understanding is relevant for multiple new techniques such as new medical treatments, implant materials, new sensors or for the processing of pharmaceutical drugs.