What is it about?
Recognition of superantigen/class II MHC complex by T cells can be inhibited by peptides derived from the Vb region of its TCR.
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Why is it important?
Peptides from the Vb region of TCR could inhibit T cell responses. This could have possible regulatory effects on the induction and regulation of immune responses.
Perspectives
These results suggest that the recognition of superantigen/class II MHC by T cells can be inhibited by peptides related to the V-beta region of its T cell receptor.
Dr Bhagirath Singh
Western University
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This page is a summary of: Inhibition of superantigen recognition by peptides of the variable region of the T cell receptor β chain, European Journal of Immunology, April 1992, Wiley,
DOI: 10.1002/eji.1830220409.
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