What is it about?

We review tips for screening methods of Transthyretin Cardiac Amyloidosis (ATTR-CM) in clinical practice and new drug therapies for ATTR-CM.

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Why is it important?

ATTR‐CM demonstrates infiltrative cardiomyopathy caused by extracellular deposition of insoluble transthyretin amyloid fibrils in the myocardium. ATTR-CM is progressive and life‐threatening if left untreated, and thus, early diagnosis is critical. However, the development of a proper strategy to reach the correct diagnosis and treatment of ATTR-CM has been long overdue.


We will be able to identify ATTR-CM early and effectively manage patients with ATTR-CM using new drug therapies.

Chief Director Hiroyuki Yamamoto
Tokyo Ika Daigaku

Read the Original

This page is a summary of: Transthyretin cardiac amyloidosis: an update on diagnosis and treatment, ESC Heart Failure, September 2019, Wiley, DOI: 10.1002/ehf2.12518.
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