What is it about?
Some patients with anorexia nervosa show liver damage that is associated not only with the elevation of aminotransferases (AST, ALT) but also with the increase in plasma levels of vitamin B12, due to leakage. We found that patients with high plasma values of vitamin B12 have higher AST and ALT values. This data suggests that plasma levels of vitamin B12 might be and early marker of liver disfunction.
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Why is it important?
Our findings might help clinicians in order to develop early and personalized treatments for preventing acute complications, also during refeeding intervention.
Perspectives
I hope that future longitudinal studies may evaluate ultrasound examination at baseline ma also during early refeeding interventions.
Dr renata nacinovich
Universita degli Studi di Milano-Bicocca
Read the Original
This page is a summary of: Paradoxical increase of plasma vitamin B12and folates with disease severity in anorexia nervosa, International Journal of Eating Disorders, November 2014, Wiley,
DOI: 10.1002/eat.22371.
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