Betaglycan function in zebrafish embryos

What is it about?

Betaglycan is a molecule present in the surface of many types of mammalian cells. In this study we isolated and characterized for the first time the gene of Betaglycan in a teleost fish, zebrafish. We also studied its function during embryonic development by reducing its expression and found that this resulted in defects in the process of blood vessel formation called angiogenesis.

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Why is it important?

This is the first time Betaglycan gene has been identified in fish, and its developmental function studied.