Reduced expressions of calmodulin

What is it about?

The roles of protein undernutrition as well as selenium (Se) and zinc (Zn) supplementation on the ability of calmodulin (CaM) to activate erythrocyte ghost membrane (EGM) Ca2+-ATPase and the calmodulin genes and protein expressions in rat’s cortex and cerebellum were investigated. We postulated that Se and Zn might be beneficial antioxidants in protecting against neuronal dysfunction resulting from reduced level of calmodulin such as present in protein undernutrition.

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Why is it important?

Our findings indicated that Se and Zn might be beneficial antioxidants in protecting against neuronal dysfunction in protein undernutrition and that Se or zinc should be incorporated in diet of children where protein undernutrition is prevalent..