What is it about?
In this review, the literature has been surveyed to provide a comprehensive coverage of the application of nitrilases in organic synthesis. Literature has also been cited to describe the isolation and/or characterization of nitrilases and related enzymes.
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Why is it important?
Hydrolase‐catalyzed reactions have been widely applied in organic synthesis. Nitrilases are an important class of hydrolase that converts naturally occurring, as well as xenobiotically derived, nitriles to the corresponding carboxylic acids and ammonia.
Perspectives
Writing this article was a great pleasure as it has co-authors with whom I have had long standing collaborations. This article also lead to the utility of nitrilases as green catalyst.
Dr Ram Singh
Delhi Technological University
Read the Original
This page is a summary of: Nitrilase and Its Application as a ‘Green’ Catalyst, Chemistry & Biodiversity, December 2006, Wiley,
DOI: 10.1002/cbdv.200690131.
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