What is it about?

Characterization of key transcription factors as molecular signatures of HPV-positive and HPV-negative oral cancers

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Why is it important?

For better prognosis, combination of AP-1, NF-κB, and STAT3 members' expression that may serve as molecular signature of HPV-positive lesions

Perspectives

Combinatorial expression of key members of AP‐1, NF‐κB, and STAT3 that participate in DNA binding and qualify as molecular signature of HPV‐positive and negative oral cancers can prove to be useful to discriminate lesions which could show better prognosis irrespective of the HPV status

DR ABHISHEK TYAGI
University of Delhi

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This page is a summary of: Characterization of key transcription factors as molecular signatures of HPV-positive and HPV-negative oral cancers, Cancer Medicine, February 2017, Wiley,
DOI: 10.1002/cam4.983.
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