What is it about?

Gastric cancer is the fifth most common malignancy and the third leading cause of global cancer death of people in the world. For better understand gastric cancer heterogeneity and develop personalized therapeutic strategies, reliable identification detailed molecular characterization of gastric cancer tissues are critical.

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Why is it important?

Our study uncovered the circRNA expression profile in human gastric cancer. Moreover, some circRNAs can stably exist in human body fluid, and has the potential to be used as novel biomarkers for the screen of high risk gastric cancer patients.

Perspectives

Dysregulated circRNAs are associated with gastric cancer. Some circRNAs can stably exist in human body fluid, and has the potential to be used as novel biomarkers for the screen of high risk gastric cancer patients.

Professor Junming Guo
Ningbo University

Read the Original

This page is a summary of: Global circular RNA expression profile of human gastric cancer and its clinical significance, Cancer Medicine, May 2017, Wiley,
DOI: 10.1002/cam4.1055.
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