What is it about?
It is about the current pathophysiological views regarding the pathophysiological role of the lipid mediator platelet-activating factor
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Why is it important?
The paper uncovers critical facts showing how a mediator initially associated with immediate hypersensitivity reactions turned into a mediator of the inflammatory response involved in invasive mycosis
Perspectives
The association of platelet-activating factor production with opsonic and non-opsonic phagocytosis explains how it is involved in both the acute inflammatory response and the activation of latent transcription factors during fungal infections
Mariano Sanchez Crespo
Consejo Superior de Investigaciones Cientificas
Read the Original
This page is a summary of: The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense, BioFactors, September 2022, Wiley,
DOI: 10.1002/biof.1888.
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