What is it about?
An easy way to synthesis of substituted quinolines is described. Simple reaction of aldehyde, amine and styrenes in the presence of iron(III) chloride afford quinolines in high yields.
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Why is it important?
The method is very simple and proceeds with easily available starting materials.
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This page is a summary of: Synthesis of Substituted Quinolines by Iron(III)‐Catalyzed Three‐Component Coupling Reaction of Aldehydes, Amines, and Styrenes, Asian Journal of Organic Chemistry, February 2014, Wiley,
DOI: 10.1002/ajoc.201300262.
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