What is it about?
In this review, we explain the transition metal catalyzed site selective alkynylation both C(sp2 )
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Why is it important?
Alkynylation reactions are one of the most sought-after synthetic methodologies due to the versatility of C-C triple bond diversifications.
Perspectives
DG-free approaches where the site selectivity and efficiency will be decided by the intrinsic functional groups or the ligands would be the future of C-H alkylation reactions. Expanding the substrate scope for enantioselective functionalization under milder conditions would be another immediate aspect that needs to be considered
Prof. Dr. Mohamed Mokhtar Mohamed Mostafa
King Abdulaziz University
Read the Original
This page is a summary of: Transition‐Metal‐Catalyzed Selective Alkynylation of C−H Bonds, Advanced Synthesis & Catalysis, October 2021, Wiley,
DOI: 10.1002/adsc.202100992.
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