What is it about?

Although the dose calculation of AXB was superior to other superposition/convolution methods in heterogeneous media, its accuracy is greatly affected by the material assignment. Therefore, a review of automatic material assignment is therefore recommended for accurate dose calculation such that the PTVs are adequately covered with optimal dose for tumor control.

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Why is it important?

Although AXB is capable of providing accurate dose calculation, its accuracy depends on the preciseness of material assignment in AXB. Our study demonstrated the serious impact of material mis-assignment in nasal cavity on dose calculation for the volumetric modulated arc therapy (VMAT) of NPC using AXB.


I hope this article would help people understand the impact of material assignment in dose calculation using AXB. Therefore, attention would be put to ensure accurate material assignment for dose calculation under AXB such that optimal dosage was given for tumor control.

Michael Cheung

Read the Original

This page is a summary of: The effect of material assignment in nasal cavity on dose calculation for nasopharyngeal carcinoma (NPC) using Acuros XB, Journal of Applied Clinical Medical Physics, June 2022, Wiley,
DOI: 10.1002/acm2.13698.
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