What is it about?
Vigabatrin, which is an anti-epileptic agent when given to mice in the developmental phase of the fetus causes birth defects, several of which are lethal.
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Why is it important?
It is important because pregnant women who have epilepsy have to continue taking anti-epileptic medications during pregnancy thereby exposing the fetuses to the deleterious effects of the drug. This paper details the these effects.
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This page is a summary of: Teratogenic effects of vigabatrinin TO mouse fetuses, Teratology, March 1997, Wiley,
DOI: 10.1002/(sici)1096-9926(199703)55:33.0.co;2-1.
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