Prediction of preterm delivery in symptomatic women using placental alpha-microglobulin-1, fetal fibronectin and phosphorylated insulin-like growth factor-binding protein-1 tests: systematic review and meta-analysis stratified by risk

Juan Carlos Melchor, Asma Khalil, Deborah Wing, Ekkehard Schleussner, Daniel Surbek
  • Ultrasound in Obstetrics and Gynecology, June 2018, Wiley
  • DOI: 10.1002/uog.19119

What is it about?

Our study confirms that the PAMG-1 test was found to have the highest the PPV and LR+ across all risk stratification groups while the NPV and LR- remained similarly high across all three biomarkers (PAMG-1, fetal fibronectin and IGFBP-1).

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