What is it about?

Countries with large populations and high consumption of turmerics (zaffron) have shown lower numbers of COVID-19 than expected. Curcumin could regulate the expression of ACE-2 - the linking protein for the virus entrance into the human cell - and also inhibit infammatory cytokines which are increased in patients with moderate and severe forms of COVID‐19.

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Why is it important?

We have discussed some of the reasons to conduct a randomized controlled trial with Curcumin to treat COVID-19 patients.

Perspectives

As the pandemic impact have been huge and we still don't have an effective drug or vaccine against SARS-CoV-2, we need to find other treatments that can avoid or limit the progression of the disease and the severe forms. Curcumin have been shown many anti-inflammatory mechanisms of action, combining a very high safety profile with relatively low costs.

PhD Marcos Renato de Assis
Faculdade de Medicina de Marília (Famema)

Read the Original

This page is a summary of: Curcumin as a potential treatment for COVID ‐19, Phytotherapy Research, June 2020, Wiley,
DOI: 10.1002/ptr.6745.
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