What is it about?
Subependymal giant cell astrocytoma (SEGA) is a slow-growing tumour originating in the walls of the lateral ventricles, usually presenting in the first two decades of life, and is often associated with tuberous sclerosis complex. However, few cases of SEGA without any clinical features of tuberous sclerosis complex have been reported.
Featured Image
Why is it important?
we present a case of an 11-year-old boy with right hemi-body weakness and headache for 1.5 years. He was diagnosed with solitary SEGA without any clinical features of tuberous sclerosis complex. Magnetic resonance imaging of the brain showed an intracranial space-occupying lesion in the left internal capsule. Biopsy was consistent with SEGA. There were no stigmata of tuberous sclerosis complex. The patient was treated with curative intent by radiotherapy.
Perspectives
SEGA should be included in the differential diagnosis of a mass near the foramen of Monro, even if there are no other features of TSC. Radiotherapy provides excellent tumour control, both as a definitive and adjuvant modality of treatment.
Dr Satyajeet Rath
All India Institute of Medical Sciences
Read the Original
This page is a summary of: Rare case of subependymal giant cell astrocytoma without clinical features of tuberous sclerosis: Case report and literature review, Precision Radiation Oncology, September 2017, Wiley,
DOI: 10.1002/pro6.24.
You can read the full text:
Contributors
The following have contributed to this page
