What is it about?
Three screening strategies based on 2D chromatography were reviewed, including traditional separation-based screening, bioactivity-guided screening and affinity chromatography-based screening. Meanwhile, in order to cover these aspects, selections of different separation mechanisms and modes were also presented.
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Why is it important?
Screening of natural bioactive components using 2D chromatography helps separation and analysis of complex samples with greater targeting and relevance, which is very important for development of innovative drug leads.
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This page is a summary of: Two‐dimensional chromatography in screening of bioactive components from natural products, Phytochemical Analysis, August 2022, Wiley, DOI: 10.1002/pca.3168.
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