Urinary 8-iso-prostaglandin F2α as a marker of metabolic risks in the general Japanese population: The ROAD study

Kanae Mure, Noriko Yoshimura, Marowa Hashimoto, Shigeyuki Muraki, Hiroyuki Oka, Sakae Tanaka, Hiroshi Kawaguchi, Kozo Nakamura, Toru Akune, Tatsuya Takeshita
  • Obesity, June 2015, Wiley
  • DOI: 10.1002/oby.21130

8-Iso-Prostaglandin F2α and Metabolic Syndrome

What is it about?

It has been reported that oxidative stress is associated with metabolic syndrome. We have examined whether urinary 8-iso-prostaglandin F2α (8-iso-PGF2α) is a reliable marker of the accumulation of metabolic risks in a cross-sectional study of the baseline characteristics of a Japanese general population cohort study: Research on Osteoarthritis/Osteoporosis Against Disability (ROAD).

Why is it important?

Our findings show that urinary 8-iso-PGF2a can be a reliable marker of impaired glucose tolerance and the accumulation of metabolic risks, especially in younger people.

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The following have contributed to this page: Dr Kanae Mure and Dr. Sakae Tanaka