What is it about?

We retrospectively analyzed 1,589 T3cN0M0 GSCC patients in the SEER database from 2004 to 2015, then to investigate the potential effect of END on overall survival (OS) and cancer-specific survival (CSS) and provide clinicians more accurate and evidence-based guidance to treat the T3, cN0 GSCC patients.

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Why is it important?

Our findings show that the wait and see strategy rather than END on T3N0M0 GSCC in the past decades, it is time to change and END is supposed to be performed on these patients for survival benefit.


I hope this article will raise awareness about the diagnosis and treatment of cN0 head and neck squamous cell carcinoma, especially whether lymph node dissection should be performed. More than anything else, and if nothing else, I hope you find this article thought-provoking.

Zhimou Cai
The First Affiliated Hospital of Sun Yat-sen University

Read the Original

This page is a summary of: Improving Survival of T3cN0M0 Glottic Squamous Cell Cancer With Elective Neck Dissection, The Laryngoscope, December 2021, Wiley,
DOI: 10.1002/lary.29973.
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