What is it about?

Engrams are physical correlates of memory storage in the brain. This article attempts to highlight the potential of Zebrafish (Danio rerio) as a prime model organism in the search for the engram, owing to its 'small' brain, transparent body and genetic tractability. Further, it also attempts to fit the defining characteristics of engram to Zebrafish, based on existing literature.

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Why is it important?

The search for engram is currently at the helm of learning and memory research. There are a few essential attributes of an engram, in terms of which we can define them. These are-persistence, ecphory, content, and dormancy. Attempts have been made before to fit these criteria to rodents and humans. However, no attempts have been made previously to check these defining criteria for Zebrafish. In this article, we attempt to investigate whether existing literature on Zebrafish learning and memory fulfill these criteria. By this, we further attempt to highlight the potential of zebrafish as a superlative model organism for dedicated engram research.

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This page is a summary of: Chasing engrams in zebrafish ( Danio rerio ), Journal of Neuroscience Research, June 2022, Wiley, DOI: 10.1002/jnr.25097.
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