Synthesis of68Ga-labeled NOTA-RGD-GE11 heterodimeric peptide for dual integrin and epidermal growth factor receptor-targeted tumor imaging

  • A new 68Ga labeled NOTA-RGD-GE11 heterodimeric peptide
  • Hung-Man Yu, Jyun-Hong Chen, Kun-Liang Lin, Wuu-Jyh Lin
  • Journal of Labelled Compounds and Radiopharmaceuticals, May 2015, Wiley
  • DOI: 10.1002/jlcr.3296

Synthesis of a tumor-targeting peptide

What is it about?

In the present study, the design and synthesis of a new RGD-GE11 peptide heterodimer for dual αvβ3 integrin/EGFR-targeted cancer imaging are described.

Why is it important?

Dual-receptor molecular imaging probes with two different heterodimeric peptides exhibit improved cancer targeting efficacy.

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The following have contributed to this page: Dr Hung-Man Yu