What is it about?

The current study now analyzes and strengthens the role of the PARP-1 ortholog in cellular proliferation of D. discoideum.

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Why is it important?

These results could be exploited to understand the conserved signaling modules in Dictyostelium and the mammalian system thereby opening new research avenues in the field of PARP-1 biology.

Perspectives

This report thus provides the first evidence wherein ADPRT1A, PARP-1 ortholog is specifically shown to be involved in controlling cell growth and cell cycle in D. discoideum.

Rasheedunnisa Begum

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This page is a summary of: Crucial role of poly (ADP-ribose) polymerase (PARP-1) in cellular proliferation of Dictyostelium discoideum , Journal of Cellular Physiology, October 2018, Wiley, DOI: 10.1002/jcp.27514.
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