What is it about?

The POLS-NIRDx is a polarization spectroscopy-based tool that can be used to differentiate between cancer and adjacent normal breast biopsy tissues by exploring the changes in the degree of linear and circular polarization of light after interacting with the tissues.

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Why is it important?

POLS-NIRDx system is cost-effective, and after certain modifications, this can be easily fitted with a microscope and perform polarization-sensitive imaging of the tissue.

Perspectives

POLS-NIRDx System can be used in other applications like for the diagnosis of myocardial fibrosis and can play a vital role in pathology-based staining without using any chemicals (i.e., label-free).

Arif Mohd Kamal
Indian Institute of Science

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This page is a summary of: Toward the development of portable light emitting diode‐based polarization spectroscopy tools for breast cancer diagnosis, Journal of Biophotonics, December 2021, Wiley, DOI: 10.1002/jbio.202100282.
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