What is it about?
Circulating Tumor Cells (CTCs) play a crucial role in early cancer diagnosis and treatment. Utilizing Dielectrophoresis technique, we have proposed a novel separation scenario for CTCs from White Blood Cells. Additionally, by studying the flow pattern and temperature inside the microchannel, the selectivity of the proposed scenario was investigated.
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Why is it important?
The proposed separation scenario relies only on electrical properties of Circulating Tumor Cells and the applied frequency which enables the inexpensive, highly selective and label free detection. It was also found that electrothermal vortices which created as a result of non-uniform temperature and non-uniform electrical properties of the media can be used to significantly enhance the separation efficiency.
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This page is a summary of: Effects of electrothermal vortices on insulator-based dielectrophoresis for circulating tumor cell separation, Electrophoresis, November 2017, Wiley,
DOI: 10.1002/elps.201700264.
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