What is it about?

The physicochemical properties of cyclopentyl methyl ether (low toxicity, high boiling and low melting points, hydrophobicity, relatively low latent heat of vaporization, and chemical stability towards a wide range of conditions, easy drying and recovery) make it a good solvent for a vast array of reactions, spanning from the different fields of catalysis to organometallic chemistry and biphasic reactions.

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Why is it important?

Solvents represent one of the major contributions to the environmental impact of fine-chemical synthesis. Therefore, the use of environmentally friendly solvents in widely employed reactions is a challenge of vast real interest in contemporary organic chemistry.


Cyclopentyl methyl ether can be successful employed in the safe and low impact setup of one-pot, multistep syntheses, a field worthy of further exploitation in the future.

Professor Ugo Azzena
Università di Sassari Dipartimento di chimica e farmacia

Read the Original

This page is a summary of: Cyclopentyl Methyl Ether: An Elective Ecofriendly Ethereal Solvent in Classical and Modern Organic Chemistry, ChemSusChem, November 2018, Wiley, DOI: 10.1002/cssc.201801768.
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