What is it about?
Cor-needle biopsies (CNBs) have larger needle diameters and cause a stronger energy effect upon the tumor tissues than Fine-needle aspiration biopsies (FNABs). The trauma against the tumor tissue is therfore larger with CNB. In a long follow up of patients up to 15 years after diagnosis a significantly higher rate of distant metastases was found after use of CNB.
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Why is it important?
If these results can be confirmed by other publications it might change the methods for tumor biopsy techniques. New methods for diagnostic microbiology markers retained from the needle of rest-blood drops in using FNAB are already in a progressive research. It might reduce the need of histology analysis, that is the main reason for using CNB.
Perspectives
The change needed in diagnostic needle biopsy techniques will reveal new even more detailed markes down to RNA levels using only slag-blood products from FNAB.
Roland Sennerstam
Department of Pathology and Oncology, Karolinska University Hospital and Karolinska Institutet, Stockholm Sweden
Read the Original
This page is a summary of: Core-needle biopsy of breast cancer is associated with a higher rate of distant metastases 5 to 15 years after diagnosis than FNA biopsy, Cancer Cytopathology, August 2017, Wiley,
DOI: 10.1002/cncy.21909.
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