What is it about?

This study compared perioperative outcomes between loco-regional and standard general anesthesia in patients with bladder cancer undergoing open radical cystectomy. A total of 60 patients were analyzed, with 15 receiving combined spinal and epidural anesthesia and 45 receiving standard general anesthesia. No significant differences were observed between groups for all intraoperative outcomes except for a shorter anaesthesia time in the study group. Pain assessment 24 hours after surgery was significantly lower in the study group. There were no significant differences in postoperative outcomes between groups. The study confirmed the feasibility, safety, and effectiveness of pure loco-regional anesthesia in these patients.

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Why is it important?

This research is important because it evaluates the feasibility, safety, and effectiveness of using loco-regional anesthesia in patients with bladder cancer undergoing open radical cystectomy (ORC). The study provides valuable insights into the use of pure loco-regional anesthesia in patients with bladder cancer, which could potentially improve patient outcomes and reduce complications. Key Takeaways: 1. The study found that loco-regional anesthesia is feasible, safe, and effective in patients with bladder cancer undergoing ORC. 2. No significant differences were observed in perioperative outcomes between loco-regional and standard general anesthesia, except for a shorter anesthesia time and greater early pain control with loco-regional anesthesia. 3. The study suggests that loco-regional anesthesia may be a viable alternative to standard general anesthesia for certain categories of patients, particularly the elderly with multiple relevant comorbidities. 4. The study highlights the need for further research to confirm the findings and to include multiple surgeons and anaesthesiologists.

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This page is a summary of: Combined spinal and epidural anaesthesia for open radical cystectomy: A controlled study, BJUI Compass, October 2023, Wiley,
DOI: 10.1002/bco2.221.
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