Cationic dendrimers for DNA binding
What is it about?
This manuscript is about molecules that can bind DNA which have potential to enable the delivery of therapeutic DNA across cell membranes (i.e. act as artificial viruses).
Why is it important?
The structures described used branched (tree-like) molecules displaying multiple copies of a biologically occuring polyamine (spermine) to bind DNA. The structures bound DNA very strongly because of this multivalent binding motif.
The following have contributed to this page: Dr John George Hardy
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