What is it about?
Impact on birthweight and subsequent diseases in adulthood
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Why is it important?
pathogenetic mechanisms explanation
Perspectives
Low birthweight is associated with a decreased risk of childhood leukaemia and an increased risk of both cardiovascular disease and all-cause mortality in adult life. Possible biological mediators include systemic innate immunity and inflammation. We tested the hypothesis that serum highly sensitive C Reactive Protein (hsCRP), a measure of both innate immunity and systemic inflammation, was positively associated with decreased birthweight. These observations provide a potential mechanism that is present at the age of three years old for the association between low birthweight and both decreased childhood leukaemia and increased cardiovascular disease in adults.
Silvia Venero
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This page is a summary of: The association of low birth weight with serum C reactive protein in 3-year-old children living in Cuba: A population-based prospective study, American Journal of Human Biology, November 2016, Wiley,
DOI: 10.1002/ajhb.22936.
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