Corneal confocal microscopy in multiple sclerosis

What is it about?

We show axonal degeneration in the cornea of patients with multiple sclerosis using the rapid non-invasive ophthalmic technique of corneal confocal microscopy. We also show increased numbers of antigen presenting cells in the cornea of patients with MS.

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Why is it important?

It provides a rapid non-invasive imaging method to identify neurodegeneration in multiple sclerosis and may be used to track progression of axonal loss and repair with therapy, particularly in clinical trials.

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