Journal of Clinical Hepatology
This article investigates the predictive value of albumin-bilirubin (ALBI), easy albumin-bilirubin (EZ-ALBI), and platelet-albumin-bilirubin (PALBI) scores for the 2-year survival of patients with hepatitis C virus-related hepatocellular carcinoma (HCV-HCC). The study retrospectively analyzed the clinical data of 174 HCV-HCC patients, followed up for 2 years, and divided them into survival and death groups based on survival status. Univariate and multivariate Cox regression analysis found that EZ-ALBI score and ascites were independent risk factors affecting patient prognosis (P<0.05), with higher EZ-ALBI scores indicating a greater risk of death (HR=1.850). The Kaplan-Meier survival curve showed significant differences in 2-year survival rates among patients with different EZ-ALBI grades (P<0.001), with rates of 90.9%, 60.2%, and 32.2%, respectively. The innovation lies in the first systematic comparison of the prognostic value of the three scoring systems in the HCV-HCC population, and the confirmation that the EZ-ALBI score, due to its simplicity and the absence of platelet parameters, is more operable and practical in clinical application. This study provides a simple and effective evaluation tool for the individualized management of HCV-related liver cancer patients.
This study explores the value of ALBI, EZ-ALBI, and PALBI scores in predicting the 2-year survival prognosis of HCV-related hepatocellular carcinoma (HCV-HCC) patients, which has important clinical significance. Firstly, these scoring systems are based on liver function indicators (such as albumin, bilirubin, and platelets) and can objectively reflect liver reserve function and portal hypertension status, being superior to the traditional Child-Pugh classification. Among them, the EZ-ALBI score has simplified and improved the ALBI, enhancing clinical operability and predictive accuracy, showing stable prognostic judgment ability in different BCLC stages and treatment modes. Secondly, the PALBI score introduces platelet parameters, further enhancing the assessment of liver cirrhosis degree and surgical risk, and has been proven to be an effective predictor of perioperative risk for liver resection. The study found through univariate Cox analysis that AST, Alb, AFP, and various scoring systems (including ALBI, EZ-ALBI, PALBI, MELD, etc.) were significantly associated with the 2-year prognosis of HCV-HCC patients, suggesting that their comprehensive application can improve predictive accuracy. Therefore, this study provides a more precise, simple, and independently predictive prognostic evaluation model for HCV-HCC patients, which helps in making individualized treatment decisions and has good clinical promotion value.
Objective: To investigate the value of albumin-bilirubin (ALBI), easy albumin-bilirubin (EZ-ALBI), and platelet-albumin-bilirubin...
